Peyronie's disease is a baffling disorder and can be difficult to treat successfully. Surgical procedures (there are many) have their drawbacks, systemic medical therapies are unpredictable and localized injections are painful. There have been reports of success with iontophoresis of corticosteroids directly into plaques and also with intralesional injection of verapamil.
Physion has developed EMDA of anti-inflammatory dexamethasone with anti-collagenic verapamil to be administered painlessly into plaques. A report of 78 patients treated demonstrated relief of pain in >90% of patients, plaque size was reduced in 50% and penile angulation was lessened in 30% of patients.
EMDA is also indicated for the treatment of: