Diabetic foot ulcers (DFUs) are a common and disabling condition among people with diabetes. DFUs have become an increasingly significant public health concern in both developed and developing countries, and are a major cause of hospitalisations and the leading cause of lower-extremity amputations in diabetics. The severity of DFUs cannot be overstated, and they create a serious risk for the individual to develop an infection or peripheral arterial disease (PAD). GlobalData epidemiologists analyzed DFU epidemiology trends in the seven major markets (7MM: US, 5EU [France, Germany, Italy, Spain, UK], and Japan) and found that infection and PAD are significant comorbidities of DFU.

Figure 1 presents the number of infection and PAD cases among the diagnosed incident cases of DFU in the 7MM in 2016.

In the 7MM, GlobalData epidemiologists forecast that the total prevalent cases of DFUs among the diagnosed diabetic population was 4,975,656 cases in 2015. In the US, there were more than 3.2 million DFU cases and in the 5EU combined there were more than 900,000 cases in 2015. In the 7MM, GlobalData epidemiologists forecast that there were more than 310,000 diagnosed incident cases of diabetic foot infection in 2015 and more than 260,000 cases of PAD in those with DFUs in the US. Similar trends are seen in Europe and Japan, with a significant proportion of DFU cases developing infections and PAD. Given the increasing prevalence of diabetes coupled with the aging population, the burden of complications related to diabetes such as DFUs and its complications are likely to increase over the next 20 years.

Details about this forecast and other discussions of the epidemiology of diabetic foot ulcers can be found in GlobalData’s EpiCast Report: Diabetic Foot Ulcers – Epidemiology Forecast to 2025 and GlobalData’s EpiCast Model: Diabetic Foot Ulcers – Epidemiology Forecast to 2025.

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GlobalData (2017). EpiCast Report: Diabetic Foot Ulcers – Epidemiology Forecast to 2025, December 2016, GDHCER143-16

GlobalData (2017). EpiCast Model: Diabetic Foot Ulcers – Epidemiology Forecast to 2025, December 2016, GDHCER143-16