The healthcare industry continues to be a hotbed of innovation, with activity driven by telemedicine, real-time diagnostics, smart hospitals and access to digital therapies, and the growing importance of technologies such as artificial intelligence (AI), the internet of things (IoT), augmented reality (AR), robotics and data management practices. In the last three years alone, there have been over 106,000 patents filed and granted in the healthcare industry, according to GlobalData’s report on Genomics in Healthcare: Molecular diagnosis biomarkers. Buy the report here.

According to GlobalData’s Technology Foresights, which uses over 443,000 patents to analyse innovation intensity for the healthcare industry, there are 200+ innovation areas that will shape the future of the industry.

Molecular diagnosis biomarkers is a key innovation area in genomics

Molecular biomarkers include biomolecules like nucleic acids and proteins that allow measurements in biological samples such as plasma, serum and cerebrospinal fluid. Diagnostic molecular biomarkers allow detection of a particular disease or disease subtype such as rapidly advancing cancer growth.

GlobalData’s analysis also uncovers the companies at the forefront of each innovation area and assesses the potential reach and impact of their patenting activity across different applications and geographies.  According to GlobalData, there are 120+ companies, spanning technology vendors, established healthcare companies, and up-and-coming start-ups engaged in the development and application of molecular diagnosis biomarkers.

Key players in molecular diagnosis biomarkers – a disruptive innovation in the healthcare industry

‘Application diversity’ measures the number of different applications identified for each relevant patent and broadly splits companies into either ‘niche’ or ‘diversified’ innovators.

‘Geographic reach’ refers to the number of different countries each relevant patent is registered in and reflects the breadth of geographic application intended, ranging from ‘global’ to ‘local’.

Patent volumes related to molecular diagnosis biomarkers

Company Total patents (2010 - 2021) Premium intelligence on the world's largest companies
Waters 173 Unlock company profile
F. Hoffmann-La Roche 163 Unlock company profile
Vanda Pharmaceuticals 142 Unlock company profile
Nestle 69 Unlock company profile
Caris MPI 67 Unlock company profile
Critical Care Diagnostics 66 Unlock company profile
Biodesix 65 Unlock company profile
SomaLogic 63 Unlock company profile
Koninklijke Philips 57 Unlock company profile
Labrador Diagnostics 49 Unlock company profile
Novartis 48 Unlock company profile
Boston Medical Center 46 Unlock company profile
Cleveland Clinic Foundation 41 Unlock company profile
Compagnie Merieux Alliance 38 Unlock company profile
NantWorks 35 Unlock company profile
Ajinomoto 33 Unlock company profile
Abbott Laboratories 31 Unlock company profile
Shiseido 30 Unlock company profile
Myriad Genetics 29 Unlock company profile
Idexx Laboratories 28 Unlock company profile
PerkinElmer 27 Unlock company profile
LipoScience (formerly LipoMed) 25 Unlock company profile
Cancer Prevention and Cure 25 Unlock company profile
St. Jude Children’s Research Hospital 24 Unlock company profile
Exact Sciences 23 Unlock company profile
Johnson & Johnson 21 Unlock company profile
Matricelab Innove 21 Unlock company profile
True Health Diagnostics 20 Unlock company profile
Assistance Publique - Hopitaux de Paris 18 Unlock company profile
Globeimmune 18 Unlock company profile
Eutropics Pharmaceuticals 18 Unlock company profile
Sysmex 17 Unlock company profile
Clinical Genomics Pathology 17 Unlock company profile
Fetal Medicine Foundation 17 Unlock company profile
Ridge Diagnostics 17 Unlock company profile
Lifecycle Technologies 16 Unlock company profile
Genocea Biosciences 16 Unlock company profile
PT Soho Global Health 16 Unlock company profile
Royal Caribbean Cruises 16 Unlock company profile
Integrated Health Leaders 16 Unlock company profile
E. Merck KG 14 Unlock company profile
MeMed Diagnostics 14 Unlock company profile
Mayo Clinic 14 Unlock company profile
Thermo Fisher Scientific 14 Unlock company profile
Vertex Pharmaceuticals 13 Unlock company profile
Danaher 13 Unlock company profile
Prometheus Biosciences 13 Unlock company profile
Eurofins Scientific 13 Unlock company profile
Biotempus 13 Unlock company profile
AbbVie 12 Unlock company profile

Source: GlobalData Patent Analytics

Waters is one of the leading patent filers in the field of molecular diagnosis biomarkers. Some other key patent filers in the field include F. Hoffman-La Roche and Vanda Pharmaceuticals.

In terms of application diversity, Boston Medical Center leads the pack, followed by Lifecycle Technologies and Johnson & Johnson. By means of geographic reach, Iddex Laboratories holds the top position, followed by Cancer Prevention and Cure and Fetal Medicine Foundation in second and third spots, respectively.

Biological markers have a wide range of applications including early diagnosis of a disease, efficient treatment selection and monitoring the output of therapeutic treatments. Genomics used with biological markers will allow analysis of genetic variations to identify the risk of diseases and track the outcome of therapeutic interventions in patients that would improve the overall quality of patient treatment.

To further understand the key themes and technologies disrupting the healthcare industry, access GlobalData’s latest thematic research report on Healthcare.

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GlobalData, the leading provider of industry intelligence, provided the underlying data, research, and analysis used to produce this article.

GlobalData’s Patent Analytics tracks patent filings and grants from official offices around the world. Textual analysis and official patent classifications are used to group patents into key thematic areas and link them to specific companies across the world’s largest industries.