View all newsletters
Receive our newsletter – data, insights and analysis delivered to you
March 7, 2011

UK Scientists Announce Breakthrough in Early Bowel Cancer Detection

Scientists at Cancer Research UK have found that DNA methylation patterns, a key process in cell development, could accurately detect early bowel cancer. It is hoped that the discovery could lead to the development of a new bowel cancer test. In a study, researchers analysed

By cms admin

Scientists at Cancer Research UK have found that DNA methylation patterns, a key process in cell development, could accurately detect early bowel cancer.

It is hoped that the discovery could lead to the development of a new bowel cancer test.

In a study, researchers analysed 261 tumour samples taken from patients with benign polyps or bowel cancer.

They found that the DNA methylation process of two genes — SFRP2 and IGF2 — identified and distinguished between tumours and benign polyps with more than 90% accuracy.

Lead author Dr Ashraf Ibrahim said that the majority of bowel cancers develop from benign polyps that turn cancerous, and this research deepens the understanding of the molecular changes behind the development.

“This first step in detecting molecular ‘flags’ for bowel cancer, could, one day, lead to a simple test to search DNA for the early signs of the disease,” Ibrahim added.

Related Companies

NEWSLETTER Sign up Tick the boxes of the newsletters you would like to receive. Get important industry news and analysis sent to your inbox
I consent to GlobalData UK Limited collecting my details provided via this form in accordance with the Privacy Policy
SUBSCRIBED

THANK YOU

Thank you for subscribing to Hospital Management