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September 5, 2011

Brainsway reports positive results from magnetic stimulation study

Brainsway has presented preliminary efficacy results of a study exploring the efficacy of deep transcranial magnetic simulation in opening the blood-brain barrier in patients with brain tumours. The study was carried out by Advanced Technologies Innovation Distribution and involved nine

By cms admin

Brainsway has presented preliminary efficacy results of a study exploring the efficacy of deep transcranial magnetic simulation in opening the blood-brain barrier in patients with brain tumours.

The study was carried out by Advanced Technologies Innovation Distribution and involved nine patients with malignant brain tumours (glioblastoma multiforme) who had undergone surgery more than a year before the trial.

The results indicated that high-intensity deep transcranial magnetic simulation induced transient opening of the blood-brain barrier in seven out of the nine patients (78%).

Blood-brain barrier opening was observed shortly after the stimulation protocol and was quantified using MRI and special protocols for blood-brain barrier permeability measurement.

The changes in blood-brain barrier permeability were measured in each patient following both active deep transcranial magnetic simulation treatment and sham stimulation.

Principal investigator Alon Friedman said, “The preliminary results suggest that the non-invasive method for opening the blood-brain barrier is safe and effective.

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“Of course, the conclusion will have to be drawn out by the final results of the trial and the results of follow up studies.”

Depending on the final results, the company may examine the possibility of performing a multicentre clinical trial to examine the safety and efficacy of deep transcranial magnetic simulation in patients with other kinds of brain tumours.

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