DNA Sequencing Technique Helps Medical Diagnosis

14 February 2010 (Last Updated February 14th, 2010 18:30)

A new DNA sequencing technique that aids in medical diagnosis has been developed by US scientists. The sequencing technique, called sequencing by denaturation (SBD), can be performed on a chip with a single integrated microfluidic device, according to University of California researcher

A new DNA sequencing technique that aids in medical diagnosis has been developed by US scientists.

The sequencing technique, called sequencing by denaturation (SBD), can be performed on a chip with a single integrated microfluidic device, according to University of California researchers.

University of California's Professor Xiaohua Huang said SBD facilitates a short sequencing run, low-cost reagents and is easy to use.

"Although the read length is quite limited, due to its simplicity, SBD has the potential to drastically bring down the cost of large-scale sequencing," Huang said.

This approach could be very useful for genotyping in the future where full sequencing is not necessary, rsc.org reports.