Researchers at the Mayo Clinic in the US have discovered two biomarkers that can predict the rate of progression in patients with progressive multiple sclerosis.

For the study, researchers looked at cerebrospinal fluid test results from a sample of 281 progressive multiple sclerosis patients seen at the Mayo Clinic from 2002 to 2007.

The study results showed a relationship between a faster disease progression and abnormally high levels of two proteins — oligoclonal bands and immunoglobulin-G.

Researchers concluded that if patients had the progressive form of multiple sclerosis with proceeding relapses and their cerebrospinal fluid results showed an elevated protein they will have a faster rate of disability.

Study researcher Junger Tang said that the study was a significant step forward in predicting disability outcomes, but further research was need to confirm the results.

Progressive multiple sclerosis is a disease of the central nervous system that can damage the brain, spinal cord and optic nerves.