Case Comprehensive Cancer Center (Case CCC) in Ohio, US, has secured a $25.5m Cancer Center Support Grant from the National Cancer Institute (NCI) of the National Institutes of Health.

This funding marks the continuation of a 38-year relationship with the NCI, dating back to Case CCC's inception in 1987.

The grant will strengthen the collaborative efforts of Case Western Reserve University, University Hospitals, and the Cleveland Clinic in advancing cancer prevention, diagnosis, and treatment.

Case CCC director Gary Schwartz said: “This award reflects the extraordinary capabilities of our research teams and the enduring strength of our consortium institutions.

“Together, we deliver scientific leadership with national reach and local relevance, driving innovation from discovery to implementation. We are proud to have received this investment that allows us to return nearly threefold to the state in the form of high-quality jobs, reduced healthcare costs, increased research activity, and strengthened biomedical infrastructure.”

The renewal of the grant, said to be the result of a 'rigorous' evaluation process, is set to offer crucial infrastructure funding.

It will support scientific leadership, research programmes, and technology platforms, as well as education and training initiatives across the partner institutions, including the Cleveland Clinic Research Institute and UH’s Seidman Cancer Center.

Cleveland Clinic CEO and president Tom Mihaljevic said: “This renewal is a testament to the transformative research, patient-centred care, and educational initiatives we are advancing together across the Case Comprehensive Cancer Center.  

“By leveraging the unique strengths of our institutions, we are driving innovation that improves lives, strengthens communities, and sets the standard for excellence in cancer treatment and prevention. This achievement inspires us to continue pushing boundaries and delivering hope to patients locally, nationally, and globally.”

The grant is expected to facilitate the establishment of new detection and prevention methods. It will also help to coordinate cancer clinical treatment studies for approximately four million people in Northeast Ohio's 15-county catchment area.

The Cancer Center Support Grant will underpin key initiatives, including multidisciplinary research across various scientific domains, the promotion of investigator-led trials, and the operation of core facilities and shared technologies for cancer researchers.

It will also support collaborations with national cooperative groups, career development programmes for emerging scientists and clinicians, and the maintenance of productive partnerships with institutions both in the US and internationally.