The Samantha Dickson Brain Tumour Trust and Cancer Research UK have teamed up to begin a multicentre Phase II clinical trial for a new surgical technique to treat brain tumours.

The GALA-5 trial being conducted at the University of Cambridge will enrol more than 60 patients with glioblastoma, to examine the tolerability and feasibility of two treatments used in combination.

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Patients are due to be given 5-amino-levulinic acid, which causes a build-up of fluorescent chemicals that will make the tumour glow, to allow for more accurate and complete removal.

The second phase of the treatment involves inplanting wafers incorporated with carmustine, a chemotherapy drug, into the cavity to help remove any remaining tumour cells.

The partnership plans to conduct a large Phase III trial if the combination therapy is found to be safe and effective.

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